UBC researcher helps map the human proteome
With 90 per cent of the proteins in the human body now mapped, Overall says scientists have a deeper understanding of how individual proteins interact to influence human health, providing insights into disease prevention and individualized medicine.
Fast and Furious: Targeting “nitro(gen) boosts” in a deadly bacterium for next-generation antimicrobials
What if bacteria also had the ability to use nitrogen for a “boost”? Alford et al. recently examined the role of a two-component system called NtrBC in Pseudomonas aeruginosa.
Coagulation Going Viral: Wisdom to Draw from Herpes Simplex Virus-1 Investigation
Cardio- and cerebro-vascular diseases remain the leading causes of death worldwide.
Soil in wounds can help stem deadly bleeding
New UBC research shows for the first time that soil silicates—the most abundant material on the Earth’s crust—play a key role in blood clotting.
Connecting the immunological dots: (Ca2+)n we do it?
When we think about how lymphocytes work, we tend to think that antigen presentation and signaling are the be-all and end-all of immune system activation and function.
A Novel Microfluidic Device to Aid in the Search for Red Blood Cell “Super-storers”
Donated red blood cell units are a vital component of patient care, supporting patients with a wide variety of disorders.
Host Tissue Factor on the Virus Envelope – A New Antiviral Target?
Viruses are small genetic bundles that hijack the metabolic processes of infected cells and can make us sick. One type of virus, called “enveloped viruses”, includes influenza, human immunodeficiency virus (HIV) and herpes simplex virus 1 (HSV-1).
A new player in blood-brain-barrier integrity
Podocalyxin (Podxl) is a protein primarily expressed on the inner surface of blood vessels and specialized kidney cells called podocytes. Although Podxl plays a critical role in kidney development and function, its purpose in blood vessels has remained cryptic.
Metaling with Chelation Therapy: Reducing Transfusion-Associated Iron Toxicity with Conjugated Drugs
Beta-thalassemias are a group of inherited blood disorders caused by a decrease in beta hemoglobin chains that can result in severe anemia, reduced oxygen supply to tissues, failure to thrive, and death.
Dampening the Inflammatory Response to P. aeruginosa Infection using a Synthetic Immunomodulatory Peptide
Antibiotic resistance and the lack of novel antibiotics pose a real threat to health, and therefore new solutions to fight resistant bacteria are required.