Earl W. Davie Symposium

Earl Davie photoThis annual 1-day symposium, in honour of Dr. Earl W. Davie, features presentations by leading experts in vascular biology, hemostasis-thrombosis, cardiovascular and neurologic disease.

Dr. Earl Davie’s research had elucidated many areas of coagulation and led to effective treatments for patients with a range of bleeding disorders. He and his colleagues devised the revolutionary Waterfall Sequence for Blood Clotting. Dr. Davie applied cutting edge technologies to identify and characterize the coagulation proteins in detail throughout the 1960s and ’70s, and subsequently isolated, sequenced, and expressed the genes for these clotting factors. For his many critical achievements, Dr. Davie had been widely acclaimed and has received numerous international awards. He was a member of the US National Academy of Science and was a Professor of Biochemistry at the University of Washington in Seattle.

Read more about Earl Davie and his legacy.


The CBR is pleased to present its 15th Annual Earl W. Davie Symposium on Tuesday, November 2, 2021 from 8 am-4:35 pm PT!

View the draft symposium program.

We anticipate that this year’s event will be held in a hybrid format, with opportunities for attendees to join us in-person at UBC Robson Square or virtually. Featured speakers include Dr. Susan Kahn, Dr. Robert Brodsky, and Dr. Victor Blanchette.

*Please note* Due to the evolving situation around COVID-19, please be aware that the format is flexible and may shift to being fully virtual. Any logistical changes will be communicated as soon as possible. Any prospective in-person attendees must comply with BC’s province-wide health regulations. We require in-person attendees to: 1) be fully vaccinated with two approved vaccine doses, 2) wear a mask, 3) be prepared to present their vaccine passport upon entry to the event. Additional requirements may be implemented if restrictions change.

REGISTER NOW for the event.

Registration deadline: Tuesday October 26, 2021, at 5 PM PT.

Please contact Dr. Dana Devine (ddevine@pathology.ubc.ca) or Mira Milutinović (mira.milutinovic@ubc.ca) with any questions.

 


Poster Presentation Guidelines for the Earl Davie Symposium

Please note that while we are aiming for some in-person activities, these may shift to virtual delivery. Any changes will be communicated as soon as possible.

Note: times listed below are tentative; event schedule to be finalized shortly.

  • Poster size: 48’’ x 36’’ maximum; landscape or portrait. 
  • Please make sure to include your contact information on the poster in case event attendees would like to contact you.
  • Please put up your poster before the first talk at 8:00 am.
  • Be prepared to give a 30 second elevator pitch about your poster: introduce yourself, what lab you’re in, the aim of your project, and an overview of the findings. The goal is to encourage the attendees to stop by your poster to learn more about your research. You do not need to prepare any slides. Elevator pitches will be from 12:15-12:25 pm--please line up on the stage to present your pitch.
  • Poster judging will occur over the coffee & lunch breaks. Each poster will be judged by 2 people, who are PDFs, RAs, or PIs. The Best Poster Award will be presented at the end of the Symposium. See the other tab for poster judging criteria.
  • Please also upload a digital copy of your poster so that online participants can also view the posters. You will be emailed a unique link to a OneDrive folder where you can upload your files. Deadline to upload poster: Wednesday, Oct. 27 at 11:59 pm PT. Note the following file details:
    • Posters should be in a PDF format.
    • File name should be in the format “Firstname_Lastname_2021 EWD poster”.

Poster judging will occur over the coffee & lunch breaks. Each poster will be judged by 2 people, who are PDFs, RAs, or PIs. The Best Poster Award will be presented at the end of the Symposium.

Each poster will be evaluated by 2 judges based on the following criteria:

  • Overall appearance: The poster is legible and not cluttered with text; any visuals used are effective.
  • Organization & flow: The components of the poster are organized in a logical flow.
  • Clarity of content: Sufficient background information is provided and the research being communicated is easy to understand.
  • Quality of poster presentation: The presenter explained the poster clearly, demonstrated content knowledge and was able to answer questions.

Participants will upload their poster and a recording of their poster presentation online. These will be shared with attendees in advance of the event, who can view the presentations at their leisure. The Best Poster Presentation will be voted on by the Symposium attendees and awarded at the end of the event.

  • During the symposium, event attendees may ask questions and engage with you on the Padlet bulletin board (more details to follow). Please check the board regularly and connect with all the participants.
  • You will be emailed a unique link to a OneDrive folder where you can upload your files. Please upload a copy of your poster and video online by Wednesday, Oct. 27, 2021 at 11:59 pm PT. Note the following file details:
    • Poster file name should be in the format “Firstname_Lastname_2021 EWD poster”. It should also be in a PDF format.
    • Video file name should be in the format “Firstname_Lastname_2021 EWD poster presentation”. The video file will be uploaded onto YouTube, so it must be in one of the following formats listed here (suggested file types: .mp4, .mov, .wmv).

Poster guidelines:

  • Size: 48’’ x 36’’ maximum; landscape or portrait. 
  • Please make sure to include your contact information on the poster in case event attendees would like to contact you.
  • Posters should be in a PDF format.

 

Video guidelines:

  • Length: 5 minutes maximum. 
  • The goal of the poster video is to mimic an in-person conference poster pitch, where you would present a short, snappy overview of your poster in front of an audience in 5 minutes or less.
  • The final presentation should be in a “shared window” layout: Your camera video should appear in the top-right corner, while your poster should be displayed on the left (further details below).
  • Video must be continuous - no edits, breaks, etc.
  • Make sure to introduce yourself before you start walking through your poster.
  • Please dress professionally for the video recording, as you would for an in-person poster presentation
  • Please structure your talk to target a broad audience.
  • We can trim the beginning and end of your video, so that the final video only includes your poster presentation and no transitions between the Zoom interface and your poster; however, we cannot provide any other edits to your video.

 

How to record your video:

  • View the instructional video below on how to properly record your poster presentation video in accordance with our guidelines.
  • Please record your presentation on Zoom. The final presentation should be in a “shared window” layout: Your camera video should appear in the top-right corner, while your poster should be displayed on the left.

  • To set up your presentation, screen share your computer on Zoom. 
  • Next, open your poster in Adobe Acrobat, and display the file using the full screen mode (on the navigation bar, select ‘View’ > ‘Full Screen Mode’).
  • To zoom in or out of the poster while presenting, use the keyboard shortcuts:
    • PC: To zoom in: Ctrl & +/=; To zoom out: Ctrl & —/-
    • Mac: To zoom in: Command & +/=; To zoom out: Command & —/-

While presenting, navigate around your poster using the mouse/arrow keys.

Tips on creating a compelling research poster:

  • Tell a story and present the ideas in a logical manner. Structure your presentation to target a broad audience.
  • When designing the poster, consider how its layout can help facilitate this storytelling and organize the ideas.
  • Cut down on text and keep the content concise. To facilitate reading, consider using visuals or bulleted lists in lieu of long paragraphs.
  • Let your poster “breathe”. Don’t be afraid of negative or white space. Too much text will decrease the readers’ attention. Use the white space to draw the readers’ attention to the most important messages.
  • Make sure text and visuals are readable without zoom when displayed at full-screen width.
  • Be selective with the use of colour. Colour can liven up the poster, but too much colour can be distracting for the reader.

 

Other Resources:


Symposium Agenda

Download the draft symposium agenda (updated Oct 15).

 

Past Symposia

2020 Program

You can view the video recordings from the symposium here:

November 17, 2020 | Zoom

Keynote Speakers:

  • Dr. Mary Cushman, MD, University of Vermont, “Understanding racial disparities in stroke”
  • Dr. Thomas Ortel, MD, PhD, Duke University, “Antithrombotic therapy in COVID-19”

Best Poster Award Winners:

  • 1st place: Jean Christophe Bélanger, PhD Candidate in Marie Lordkipanidzé's lab at the University of Montréal, "The Brain-Derived Neurotrophic Factor mitigates the association between platelet dysfunction and cognitive impairment in coronary artery disease"
  • Runner-Up: Nancy Yang, MSc student in the Côté lab at UBC, "A Proposal: How Much Is Too Much? The Burden Of Chronic/Latent Viral Infections on Aging"
  • Runner-Up: Andy An, PhD Candidate in the Hancock lab at UBC, "The role of S100A9 on macrophage cellular reprogramming in the context of sepsis"

2019 Program

November 13, 2019 | UBC Robson Square, 800 Robson Street, Vancouver, BC

Below you can view the photo highlights and videos from the presentations:

Keynote Speakers:

  • Dr. Nancy Berliner, MD, Harvard Medical School, “Everything you need to know about hemophagocytic lymphohistiocytosis"
  • Dr. Robert Montgomery, MD, Versiti – Blood Center of Wisconsin, “Cellular relationships ofVWF with FVIII – what we know and don’t know”

Best Poster Award Winners:

  • 1st place: Neha Sharma, PhD student in Liaw lab at Thrombosis & Atherosclerosis Research Institute, "Exploring the effectiveness of DNA and Glycosaminoglycans as inhibitors of histones"
  • 2nd place: Marie-Soleil Smith, MSc student in Côté lab at UBC, "Investigating the relationship between HIV antiretrovirals and human embryonic stem cell differentiation"
  • 3rd place: Chanel La, PhD candidate in Kizhakkedathu lab at UBC, "Macromolecular polyphosphate inhibitors for treatment of thrombosis"

2018 Program 

November 15, 2018 |  SFU Segal Building, 500 Granville Street, Vancouver, BC

Below you can view the photo highlights and videos from the presentations:

Keynote Speakers:

  • John Griffin, MD, PhD, The Scripps Research Institute, “Activated protein C: Biased for translation and neuroprotection”
  • Maureane Hoffman, MD, PhD, Duke University, "Tissue specific hemostasis. The next frontier?”

Best Poster Award Winners:

  • 1st place: Stefanie Novakowski, PhD candidate in Kastrup lab, for her work on “Delivery of mRNA to platelets using lipid nanoparticles”
  • 2nd place: Tammy Truong, PhD candidate in Medical Sciences at McMaster University, “Identification of the histidine-rich glycoprotein domain responsible for its inhibition of factor XIIa”
  • 3rd place: Emel Islamzada, MSc student in Ma lab, “Deformability as a Biomarker for the Quality of Stored Red Blood Cells”

2017 Program

November 16, 2017 | Sheraton Vancouver Wall Centre, 1088 Burrard Street, Vancouver, BC
Below you can view the photo highlights and videos from the presentations:

Earl W. Davie Symposium - Nov 16, 2017 - Part 1
Earl W. Davie Symposium - Nov 16, 2017 - Part 2
Earl W. Davie Symposium - Nov 16, 2017 - Part 3
Earl W. Davie Symposium - Nov 16, 2017 - Part 4
Photos

Keynote Speakers:

  • Katherine High, MD, President, CSO, Spark Therapeutic, “Gene therapy for genetic disease: can genes become medicines”
  • James Morrissey, PhD, University of Illinois at Urbana-Champaign, “Polyphosphate in hemostasis and thromboses”

2016 Program

November 17, 2016 | Segal Building, 500 Granville Street, Vancouver BC

Read the recap of the EWD Symposium 2016.

Keynote Speakers:

  • Dr. John W. Weisel, Professor of Cell and Developmental Biology, Perelman School of Medicine
  • Dr. Nigel Key, Professor of Medicine and Pathology, Chief of the Section of Classical Hematology, and the Director of the UNC Hemophilia and Thrombosis Center

Best Poster Award Winners:

  • First Place: Bryan Lin, PhD candidate in Dr. Pryzdial's lab
  • Second Place: Frank Lee, MD/PhD student in Dr. Pryzdial's lab
  • Third Place: Vivienne Chan, PhD candidate in Dr. Kastrup's lab

Below you can view the videos from the symposium:

Earl W Davie Symposium - Segment 1

Earl W Davie Symposium - Segment 2

Earl W Davie Symposium - Segment 3

2015 Program    

November 19, 2015 | SFU Harbour Centre, 515 West Hastings Street, Vancouver, BC

Read the recap of the EWD Symposium 2015 and an interview with the CBR Directors about the event.

Below you can view the photo highlights and videos from the presentations:

Morning Sessions Video

Afternoon Sessions Video

See photos from the event

Keynote Speakers: 

  • Dr. Ken Kaushansky, MD, Dean of Medicine, Stony Brook, NY | “Thrombopoiesis”
  • Dr. Björn Dahlbäck, MD, PhD, Lund University | "Novel Insights into the Role of Factor V as a Regulator of Blood Coagulation"

2014 Program    

November 13, 2014 | SFU Harbour Centre, 515 West Hastings Street, Vancouver, BC

For videos from the 2014 Earl W. Davie Symposium please click here!

Part I:
0:00:00 - 0:05:10 | Dr. Ed Conway, Opening Remarks|
0:05:11 - 0:47:40 | Dr. Uller Hedner "Perspectives on the clinical use of factor VIIa"
0:47:44 - 1:22:00 | Dr. David Gailani "Factor XI and Prekallikrein"
1:22:06 - 1:36:16 | Dr. Becky Woodruff "Targeting the contact pathway with RNA aptamers"
1:36:18 - 1:48:50 | Dr. Jerome Robert "Tissue engineering of the cerebrovasculature"
1:48:52 - 1:57:31 | Dr. Sandra Degen "Reflections on my thesis advisor, Earl W. Davie"

Part II:
0:00:00 - 0:35:10 | Jay Kizhakkedathu "Manipulating coagulation with polymers: Inhibitors for heparins and polyphosphates"
0:35:17 - 1:29:35 | Phil Majerus "Aspirin"
1:29:43 - 1:54:01 | 'Shotgun' Talks

Part III:
0:00:00 - 0:12:15 | Antoine Dufour “Macrophage MMP12: Pleiotropic roles in inflammation revealed by TAILS terminomics”
0:13:00 - 0:20:30 | Neil MacKenzie "Cathepsin mediated digestion of elastin in vascular calcification"
0:20:34 - 0:28:10 | Matthew Solomonson "Structural study of protein secretion system essential to Mycobacterium tuberculosis infection"
0:28:12 - 0:33:52 | Diana Canals "Podocalyxin is a key regulator of breast cancer progression and metastasis"
0:33:52- 1:13:32 | Jay Degen "Hemostatic factors in inflammatory disease"
1:13:37 - 1:41:37 |Mel Krajden "EBOLA: Facts, fiction and fears"

Part IV:
0:00:00 - 0:42:50 | Denisa Wagner "Inflammation and thrombosis: Tangled up in NETs"
0:42:55 - 1:12:57 | Ed Pryzdial "Grand theft platelet: Dengue virus stories"

Keynote Speakers: 

  • Dr. Phil Majerus, MD, MD, Washington University School of Medicine, St. Louis | "Aspirin"
  • Dr. Denisa Wagner, PhD, Boston Children's Hospital, Harvard Medical School | "Inflammation and thrombosis: Tangled up in NETs"

2013 Program    

November 14, 2013 | SFU Segal Building, 500 Granville Street, Vancouver, BC

For videos from the 2013 Earl W. Davie Symposium please click here!

Part I:
0:00:00 – 0:06:00 | Dr. Ed Conway, Opening Remarks
0:06:02 – 0:58:00 | Dr. Edmond Fischer "The origin of reversible protein phosphorylation as a regulatory mechanism"
0:58:05 - 1:35:50  Dr. David Motto "Hemostasis and thrombosis, new questions raised from mouse models"
1:36:03  - 1:48:40 | Dana Kyluik-Price "Direct and indirect immunocamouflage of blood antigens"
1:49:00- 2:09:05 | Eric Ouellett "High-fidelity SELEXion: an improved platform for discovery of aptamer-based therapeutics"

Part II:
0:00:00 – 0:59:50 | Barry Coller "From the rivers of Babylon to the coronary bloodstream: The αIIbβ3 Story"
0:59:54 – 1:19:36 | Shot-gun talks

Part III:
0:01:20 – 0:19:33 | Jonathan Foley "Diverse properties of polyphosphates in the blood"
0:19:44 – 0:56:28 | Margaret Rand "Flipping and flopping and blocking platelet procoagulant phosphatidylserine"
0:56:30  – 1:33:38 | Sara Israels "Developmental hemostasis: Neonatal platelets acting their age"

Part IV:
0:01:20 – 0:24:10 | Christian Kastrup "Clotting the unclottable: halting severe hemorrhaging, and clotting without fibrinogen"
0:24:23 – 1:33:34 | Shaun Coughlin "Protease activated receptors – a 3-dimensional view"
1:33:36 – 1:41:15 |Closing remarks

Recap

November 14, 2013 marked the 7th Annual Earl W. Davie Symposium, hosted by the CBR and sponsored by Novo Nordisk. It was a memorable event, hosted in the historic old Bank of Montreal building in downtown Vancouver, with over 180 attendees, a range of entertaining and stimulating speakers, excellent posters, delicious food and fine wine.

Arguably, one of the major discoveries in medicine in the latter half of the 20th century was made by Dr. Earl Davie who, in 1964, proposed the waterfall sequence for blood clotting. Although our understanding of the biochemical events surrounding coagulation has evolved since then, the major concepts have been and continue to be the basis for currently used diagnostic tests and therapies, in coagulation and in other diseases. The impact of Dr. Davie’s work is indeed, immeasurable, and we are grateful to have the opportunity to honour him each year with this annual symposium that carries his name. Read More...

Keynote Speakers

  • Dr. Shaun Coughlin, MD, PhD, Professor of Medicine, University of California, San Francisco | "Protease activated receptors – a 3-dimensional view"
  • Dr. Barry Coller, MD, PhD, Professor of Medicine, Rockefeller University | "From the rivers of Babylon to the coronary bloodstream: The αIIbβ3 Story"

2012 Program  

November 13, 2012 | Four Seasons Hotel, 791 West Georgia Street, Vancouver, BC

Recap

November 13, 2012 marked the 6th Annual Earl W. Davie Symposium, hosted by the CBR and sponsored by Novo Nordisk. It was a memorable event, with over 200 attendees, a range of entertaining and stimulating speakers, excellent posters, delicious food and fine wine.

Arguably, one of the major discoveries in medicine in the latter half of the 20th century was made by Dr. Earl Davie who, in 1964, proposed the waterfall sequence for blood clotting. Although our understanding of the biochemical events surrounding coagulation has evolved since then, the major concepts have been and continue to be the basis for currently used diagnostic tests and therapies, in coagulation and in other diseases. The impact of Dr. Davie’s work is indeed, immeasurable, and we are grateful to have the opportunity to honour him each year with this annual symposium that carries his name.

Keynote Speakers

  • Dr. Charles T. Esmon, PhD, Howard Hughes Investigator and Member of Oklahoma Medical Research Foundation | "Hype about histones in infections and inflammation
  • "Dr. David Ginsburg, MD, PhD, Howard Hughes Investigator, Professor of Medicine, University of Michigan | "Infectious diseases, coagulation and fibrinolysis"

2011 Program  

November 3, 2011 | Vancity Theatre, 1181 Seymour St  Vancouver, BC V6B 2E8

Keynote Speakers

  • Dr. Steve Olson | "Regulation of blood clotting by serpin family protein protease inhibitors and their cofactors"
  • Dr. Uri Seligsohn"The role of factor XI in hemostasis and thrombosis"

2010 Program   

November 4, 2010 | Vancity Theatre, 1181 Seymour St  Vancouver, BC V6B 2E8

Keynote Speakers:

  • Dr. Ken Mann | "Blood Clotting: The Good, the Bad and the Ugly"
  • Dr. Désiré Collen | Biopharmaceutical Drug Development between Academia and Industry