Research

A novel antibiotic-host defense peptide conjugate with multiple talents

A novel antibiotic-host defense peptide conjugate with multiple talents

Etayash and colleagues identified a novel vancomycin-innate defence regulator conjugate (V-IDR1018) as a promising candidate for the treatment of bacterial infections.

Bags of blood on a white background. Blood types seem to be A, B and O.

Revisiting cold-stored platelets: An effort to improve patient care and storage feasibility

Wayne Zhao of the Devine Lab shares his work on platelet storage conditions, and whether we should consider revisiting cold-stored platelets.

Glass vials with blood. Image Courtesy of UBC Science. Illustrates the idea of creating universal blood-type organs for transplant.

Creating universal blood-type organs for transplant

Dr. Jayachandran Kizhakkedathu’s team and collaborators are creating universal blood-type organs for transplant.

Blood vacutainer tubes on the left, white text on a dark red background on the right that reads: "Sepsis: The End is Just the Beginning"

Sepsis: The end is just the beginning

Andy An explains the critical need to study sepsis and post-sepsis syndrome, and how COVID-19 has brought new attention to both.

UBC researchers lead $24 million project to treat spinal cord injury

UBC researchers lead $24 million project to treat spinal cord injury

Dr. Karen Cheung is part of the Mend the Gap project, which will develop soft gels to help regrow nerve fibres in an injured spinal cord.

Ambulance with sirens flashing driving quickly past what looks like a hospital setting.

Machine learning and AI used to rapidly detect sepsis, cutting risk of death dramatically

A groundbreaking advance in quickly detecting sepsis using machine learning has been pioneered by researchers in the Hancock Lab.

Pills and medication

UBC researchers train computers to predict the next designer drugs

Research from Dr. Michael Skinnider and Dr. Leonard Foster have trained computers to predict the next designer drugs before they are even on the market, technology that could save lives.

UBC-led researchers uncover how the novel coronavirus escapes a cell’s antiviral defenses

UBC-led researchers uncover how the novel coronavirus escapes a cell’s antiviral defenses

A UBC-led research team has uncovered how the virus responsible for causing COVID-19 escapes destruction in infected cells, allowing SARS-CoV-2 to persist and continue spreading in the human body.

Image of bacteria on a black background

Warding Off the Post-Antibiotic Era: Stimulating the Pursuit to Visualize a Common Antibiotic Target

In a paper by Caveney et al., the antibiotic-free structure of a penicillin-binding protein from the human pathogen Escherichia coli was determined using single-particle cryo-EM.

Illustration of a microscopy image of an endothelial glycocalyx. Illustration by the Centre for Blood Research (CBR).

Developing microchip technology to better answer questions about the endothelial glycocalyx

The Kizhakkedathu Lab and their collaborators developed an improved method for studying glycocalyces by using microfluidic chip technology.