Research

UBC Medicine innovators join HATCH Venture Builder to develop transformative health solutions

UBC Medicine innovators join HATCH Venture Builder to develop transformative health solutions

Three start-up ventures founded by faculty of medicine community members have joined UBC’s HATCH Venture Builder to help bring innovative health solutions from the lab into the clinic.

Unconventional secretion of the SARS-CoV-2 main protease opens the door for new extracellular biology in viral infection

Unconventional secretion of the SARS-CoV-2 main protease opens the door for new extracellular biology in viral infection

In a recent Cell Reports paper from the Overall Lab, Grin et al. reveal the unconventional secretion of the SARS-CoV-2 main protease, 3CLpro, from infected cells into the extracellular milieu through gasdermin (GSDM)-D and GSDME pores activated by caspases.

Too Much of a Good Thing? Iron’s Role in Accelerating Myelodysplastic Syndromes

Too Much of a Good Thing? Iron’s Role in Accelerating Myelodysplastic Syndromes

In a recent Blood commentary, Dr. Heather Leitch from the CBR highlights groundbreaking research from Antypiuk et al2 that links iron overload with the worsening of MDS symptoms, including bone marrow failure and increased risk of leukemia.

Katerina spends most of her time at the lab working in a biological safety cabinet, which is a sterile environment for cell culturing.

Lay Science Writing Competition 2024: Understanding graft versus host disease (GvHD)

In this blog, Katerina Rosenflanz, the author of the first-prize winning entry, provides some behind-the-scenes insights into the preparation of her LSWC submission.

The Role of Filamin A in Blood Clotting: How Platelets Change Shape to Stop Bleeding

The Role of Filamin A in Blood Clotting: How Platelets Change Shape to Stop Bleeding

The Kim lab in the CBR has been studying how platelets change shape, specifically focusing on a protein called Filamin A (FLNA), which plays a crucial role in the shape-shifting process.

Lay Science Writing Competition 2024: Research ensures innovation and safety go hand in hand for stem cell transplantation

Lay Science Writing Competition 2024: Research ensures innovation and safety go hand in hand for stem cell transplantation

Postdoctoral fellows Drs. Chaahat Singh and Giorgia Caspani describe their research in the Jefferies lab and their experience preparing their written LSWC entry which claimed second prize in this year’s competition!

Blood vessel-like coating could make medical devices safer for patients

Blood vessel-like coating could make medical devices safer for patients

University of B.C. researchers have developed a groundbreaking coating that could make medical devices safer for millions of patients, reducing the risks associated with blood clots and dangerous bleeding.

The Gut-Brain Link in Psychedelics: A New Path to Mental Health?

The Gut-Brain Link in Psychedelics: A New Path to Mental Health?

Psychedelics, such as psilocybin and LSD, have gained attention as promising therapies for psychiatric disorders like depression and PTSD. A recent review by the Jefferies lab may play a crucial role in how psychedelics alter mood and behaviour.

Lay Science Writing Competition 2024: Evaluating umbilical cord blood transfusion efficacy and safety in neonates

Lay Science Writing Competition 2024: Evaluating umbilical cord blood transfusion efficacy and safety in neonates

The 2024 Lay Science Writing Competition offered in partnership with CBS provides research trainees an opportunity to exercise and enhance their science communication skills. Congratulations to Mahsa Yazdanbakhsh, author of the third prize-winning entry!

Amenorrhea in Women with HIV: Unveiling Key Risk Factors for Menstrual Health

Amenorrhea in Women with HIV: Unveiling Key Risk Factors for Menstrual Health

New research from the UBC Centre for Blood Research and collaborators throughout UBC, examines the prevalence of early prolonged secondary amenorrhea in women with HIV and its associated biopsychosocial factors.