Research

Lipid Nanoparticle Freight Comparison 

Lipid Nanoparticle Freight Comparison 

The Kastrup group compared the effects of two ionizable cations lipids for RNA therapies targeting the liver

Jefferies Lab publication “A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours”

Jefferies Lab publication “A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours”

Publication from Dr. Jefferies Lab: “A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours”Published: May 15, 2023 https://doi.org/10.3389/fphar.2023.1119607

Jefferies Lab publication “The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain”

Jefferies Lab publication “The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain”

Publication from Dr. Jefferies Lab: The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain.Published: April 20, 2023 https://www.nature.com/articles/s41598-023-30054-8

Jefferies Lab publication “Specific cannabinoids revive adaptive immunity by reversing immune evasion mechanisms in metastatic tumours”

Jefferies Lab publication “Specific cannabinoids revive adaptive immunity by reversing immune evasion mechanisms in metastatic tumours”

Publication from Dr. Jefferies Lab: “Specific cannabinoids revive adaptive immunity by reversing immune evasion mechanisms in metastatic tumours”Published: Feb 22, 2023 https://doi.org/10.3389/fimmu.2022.982082

Innovative treatment targets blood clots without increased bleeding risk

Innovative treatment targets blood clots without increased bleeding risk

The development of MPI 8 represents a major breakthrough in the field of blood clot prevention and treatment, said Dr. Jayachandran Kizhakkedathu.

Hot bees are dead bees

Hot bees are dead bees

With the support of a CBR Transition Grant, Dr. Alison McAfee is investigating how different types of bees withstand hot temperatures.

New Treatment Option for a Deadly Muscle Disease: An Arduous Journey for the Advancement of Medicine

New Treatment Option for a Deadly Muscle Disease: An Arduous Journey for the Advancement of Medicine

Dr. Farshad Babaeijandaghi and the Rossi Lab have discovered a new drug that could help treat Duchenne’s muscular dystrophy.

Emerging artificial intelligence methods to assess transfusion quality

Emerging artificial intelligence methods to assess transfusion quality

Research from Dr. Hongshen Ma’s lab describes how machine learning and artificial intelligence can help assess transfusion quality.

CBR scientists receive federal support to advance mRNA vaccine technologies

CBR scientists receive federal support to advance mRNA vaccine technologies

Dr. Leonard Foster and Dr. Natalie Strynadka have received $11.1 million for research on the delivery and efficacy of mRNA vaccines.

“Squeeze-ability” of a red blood cell: The deformability of red blood cells is a useful biomarker for storage quality

“Squeeze-ability” of a red blood cell: The deformability of red blood cells is a useful biomarker for storage quality

CBR scientists found that red blood cell deformability – its ability to squeeze and change shape – could be a useful biomarker for storage quality.