The First Targeted Gene Therapy Approved in North America: Luxturna
RPE65-mediated inherited retinal dystrophy leads to severe deterioration of vision and complete blindness in early adulthood. A small subgroup of patients, approximately 1000 people in the United States, have mutations in both paternal and maternal copies of the RPE65 gene that encodes retinoid isomerohydrolase.
31st Annual Canadian Society for Immunology Meeting
Thanks to the Centre for Blood Research for providing me with the CBR Postdoctoral Fellow Travel Award. Because of this travel award, I had the opportunity to attend the 31st Annual Canadian Society for Immunology Meeting (CSI) for the first time.
2018 Michael John Page Postdoctoral Fellow Award
On Wednesday October 17th, Dr. Jennifer Grants was presented with the 2018 Michael John Page Postdoctoral Fellow Award by the Department of Biochemistry & Molecular Biology (BMB) and the Centre for Blood Research (CBR).
Building Resilience in Graduate School
When I started graduate school at UBC in 2012, I thought I was prepared. I had excellent marks, publications from research done as an undergraduate student, and even an NSERC award.
Graduate Award Program – Brought to You by the CBR
One of the goals of the Centre for Blood Research (CBR) revolves around education. The CBR actively promotes and fosters the young blood that will enter the highly multi-disciplinary field that is blood research.
The Box
At the Centre for Blood Research, my research typically embraces out-of-the-box thinking, addressing biological problems from an open-minded standpoint to gain novel insights. However, recently, I was forced to focus on what’s inside the box, namely the Canadian Blood Services box for transporting human blood products.
Paradigm Shifts in Cell Wall Biogenesis Understanding
Antibiotic resistance has become a major issue in recent years, and is believed to be directly linked to the livestock industry which accounts for ~80% of antibiotic use in North America. Frighteningly, this is expected to rise by nearly 70% globally by 2030.
Gene-trap Mutagenesis Identifies a Crucial Role for a Cryptic Member of the ABC Superfamily
The ATP-binding cassette (ABC) super-family of proteins is one of the largest families of proteins to have representatives in all living organisms from prokaryotes to humans.
CBR Research Day 2018: In Review
On Thursday, August 16, the Centre for Blood Research hosted their annual Research Day, an afternoon event recognizing the achievements of those involved in the CBR Summer Studentship Program. The program provides undergraduate students with the opportunity to undertake a basic or clinic research project by partnering with CBR researchers.
Profile: Rhys Watson
Rhys participated in the CBR Job Shadow Program back in February 2017, working closely with Bryan Lin and Frank Lee, PhD candidates from the Pryzdial lab. Read on to find out more about Rhys, his learning experience at CBR, and his advice in engaging with people living with Hemophilia A.