Killing us with Sweetness: Understanding the Role of Protein Glycosylation in Bacteria-related Sepsis
A. baumannii infections cause ventilator-associated pneumonia and wound infections, leading to life-threatening bacteremia/sepsis. How does it resist the host’s immunological response?
From the CBR Director’s Chair: Reflecting on 2015 – a Foundation for 2016!
As we rapidly gear up for 2016, it’s worth reflecting on some of our accomplishments in 2015, which, from several vantage points, proved to be an exciting and a highly productive year.
Let Rare Mutations Speak: Novel Mechanisms in Immune System Regulation
Chris Overall lab investigated a unique mutation in the MALT1 gene, which lead to a patient that paradoxically had a poor response to infection and autoimmune symptoms.
Q & A with Ed and Ed
Last week, a budding reporter and Conway Lab Manager, Victor Lei sat down with CBR’s Director Ed Conway and CBR Associate Director Ed Pryzdial to talk about the 9th annual Earl Davie Symposium.
Earl W. Davie Symposium 2015 – in Review
To honor the illustrious career of Dr. Earl W. Davie, the CBR hosts the annual Earl Davie Symposium, showcasing endeavors in the fields of vascular biology, hemostasis-thrombosis, cardiovascular and neurologic disease, by both local and international experts. Read the full review of the day.
Dentist with a Lab Coat
On a cold Monday morning, nearly a million health-care providers in Canada are going to see patients. A small number of them, less than one in 200, also work as a scientist. Dr. Hugh Kim of the Centre for Blood Research is one of the newest clinician-scientists in British Columbia.
Focus on Dental Pulp: the Overall Lab Discovers New Proteins
Dr. Chris Overall and his team recently published a study focused on human dental pulp, reporting the most comprehensive snapshot of any dental tissue so far. It was featured in the Editorial of the Human Proteome Project Special Issue published by the Journal of Proteome Research for the HUPO-2015 world congress.
Going Against the Flow: Self-Fuelled Microparticles Deliver Cargo through Flowing Blood to Stop Hemorrhage
James Baylis, a PhD student in Dr. Christian Kastrup lab at the CBR, spearheaded a collaborative study that was recently published in the journal Science Advances characterizing a self-propelled drug delivery system capable of penetrating deep into the wound site.
Searching for Alternative Plasticizers for Red Blood Cell Storage Bags
This comparative study suggests that the current DEHP plasticizer is best at preserving RBC quality, and DINCH, an alternative plasticizer may also be feasible for blood storage bag production.
Dr. Conway invited to co-lead a Canadian Network on Venous Thromboembolism
Ed Conway, the Director of the UBC Centre for Blood Research (CBR), will co-lead the translational/basic science platform of a new national research network focused on venous thromboembolism (VTE) — the first such network in the world.