Unlocking a mystery: How a healthy microbiome protects babies from chronic inflammation
This story is re-published from the Canadian Institutes of Health Research website. Photos credited to Phillip Chin. Link to original story: https://cihr-irsc.gc.ca/e/54370.html. Why does a sanitized environment protect us from infections but seem to increase the chances of developing chronic inflammatory diseases such as asthma and eczema? Why does exposure to some bacteria appear to […]
Welcome 2025 Students!
We are so excited to welcome 21 summer students to this year’s CBR-LSI Summer Studentship Program. Over the next four months, these students will take part in exciting workshops alongside their research projects. Learn more about them and their research below: Alice Hong PI: Dr. Carolina Tropini I just completed my 5th year in Biomedical […]
Unconventional secretion of the SARS-CoV-2 main protease opens the door for new extracellular biology in viral infection
In a recent Cell Reports paper from the Overall Lab, Grin et al. reveal the unconventional secretion of the SARS-CoV-2 main protease, 3CLpro, from infected cells into the extracellular milieu through gasdermin (GSDM)-D and GSDME pores activated by caspases.