UBC graduation ceremony.
Marie-Soleil Smith is a recent PhD graduate in Dr. Hélène Côté’s lab. Marie-Soleil has been heavily involved with the CBR Knowledge Translation committee and the Health & Wellness Committee. She’s helped organize many CBR events and was a long-time writer and editor for CBR blogs. We’re excited to share her journey at the CBR & wish her all the best in her next chapter.
What inspired you to pursue graduate studies at UBC?
Having completed my undergraduate degree in Microbiology and Immunology, I have always been fascinated by the inner workings of the disease process. UBC is a hub of cutting-edge research, and I was particularly inspired by my PhD supervisor, Dr. Hélène Côté. Her groundbreaking work with HIV antiretroviral therapy and women’s health was directly in line with my research interests. I was especially excited to work on a project utilizing human embryonic stem cells, a model I was eager to explore further.
What was your research about?
My PhD research utilized human embryonic stem cells to identify the effects of HIV antiretrovirals on embryonic development during pregnancy, particularly their impact on cellular and mitochondrial health as well as on early embryonic differentiation. My work aimed to improve health outcomes in infants exposed to HIV drugs in utero by addressing critical gaps in our understanding of HIV treatment safety in the context of pregnancy. I explored the molecular mechanisms underlying drug toxicity and identified potential safer therapeutic options for the treatment of HIV in women of reproductive age.
December 2023 lab party at Helene’s home.
You’ve been an active member in several committees at the CBR over the past years. Why did you join and what did you enjoy about them?
I conducted by PhD research at the UBC Hospital, and although it is geographically very close to the CBR, it often felt like worlds away. I first got involved with the CBR Health and Wellness committee after attending a very enjoyable and lively Aqua Zumba activity they organized in 2019. This experience opened the flood gates, leading me to meet many new people engaged in different but fascinating research, fostering a heightened sense of community. To further broaden my scientific network and contribute to the vibrant research community at UBC, I joined the Knowledge Translation committee to flex my writing and editing muscles. Being part of these committees allowed me to collaborate with a diverse group of researchers and professionals, enhancing my interdisciplinary knowledge and skills. I particularly enjoyed organizing activities such as the Stair Challenge with the Health and Wellness committee and editing a broad scope of fascinating articles produced by the Knowledge Translation committee.
August 2023 CBR Research Day with fellow CBR peers.
Can you share one of the best memories you’ve had being a part of the CBR?
One of my best memories was with my CBR Graduate Award Program (GAP) cohort in the early days of the COVID-19 pandemic. One of the tasks assigned to GAP students is to organize an event. Our group originally planned to host an in-person video and board game night on March 19, 2020. However, due to the safety restrictions put in place, our event was canceled. Quick thinking and a dedication to giving back to the CBR community led us to shift from hosting an event to creating care packages for CBR members. Despite this pivot, the adversity we faced together highlighted our teamwork and resulted in a service that was well received by the community.
What is one piece of advice you would give a new grad student?
My advice to new grad students is to actively seek out and engage with the various opportunities that UBC and Vancouver have to offer. Whether it’s joining clubs, attending seminars, or exploring the city’s natural beauty, immersing yourself in these experiences will enrich your graduate journey. Additionally, don’t be afraid to ask for help and collaborate with others. Building a support network and working with peers can significantly enhance both your personal and academic growth.
What’s next for you?
April 2023 Canadian Association for HIV Research (CAHR) conference in Quebec City.
I’m excited to announce my move to Toronto and am actively seeking new opportunities! My primary goal is to further develop my expertise in stem cell biology while continuing to explore the fascinating intersection of infectious diseases and women’s health. I’m eager to apply my knowledge to innovative and challenging projects that can make a meaningful impact.
Is there anyone you’d like to thank or anything else you’d like to add?
I would like to express my heartfelt gratitude to my supervisor, Dr. Hélène Côté, for her unwavering support and guidance throughout my PhD journey. I also want to thank my family, friends, and colleagues for their encouragement and companionship. Lastly, I am grateful to the UBC and CBR communities for providing such a stimulating and supportive environment for my research and professional development.