Peter Schubert


Held Positions

  • Principal Investigator, Centre for Blood Research and
    Clinical Associate Professor, Department of Pathology and Laboratory Medicine, University of British Columbia
  • Principal Manager, netCAD Blood4Research Facility and
    Component Scientist, Product and Process Development, Centre for Innovation, Canadian Blood Services

Research Interests

[numbers in brackets refer to the publication list below]

  • Impact of donor characteristics on blood component quality [1, 2] and transfusion outcome [3, 4]
  • Impact of modulation on current blood product manufacturing [5] towards NextGen blood products such as pathogen reduced platelets [6-16], platelet additive solutions [17] or pathogen reduced whole blood [18]
  • Blood product characterization using biochemistry and proteomic approaches to unravel signal transduction pathways to develop improved in vitro quality assessment tools [19-25]
  • Collaborations to further understanding blood and blood component safety aspects [26-28]

Selected Publications

  1. Chen D, Schubert P, Devine DV (2017) Proteomics of red blood cells from donors exhibiting high hemolysis: membrane-associated proteins are involved in oxidative damage, Transfusion, 57(9):2248-56.
  2. Schubert P, Coupland D, Nombalais M, Walsh GM, Devine DV (2016) Rho/ROCK signaling contributes to sex differences in the activation of human platelets, Thromb Res, 139:50-5.
  3. Schubert P, Culibrk B, Karwal S, Slichter SJ and Devine DV (2012) Optimization of platelet concentrate quality: Application of proteomic technologies to donor management, J Proteomics, 76(1):329-336.
  4. Schubert P., Kelly A., Culibrk B., Cardigan R. and Devine D.V. (2021) Proteomic analyses of samples from a clinical trial revealed biomarkers for the prediction of transfusion outcome, in preparation
  5. Mastronardi C, Schubert P, Levin E, Bhakta V, Yi Q, Hansen A, Stewart T, Jenkins C, Lefresne W, Sheffield WP and Acker JP (2013) Process improvement by eliminating mixing of whole blood units after an overnight hold period to component production using buffy coat method, J Blood Transfus, 2013:154838.
  6. Schubert P, Culibrk B, Coupland D, Scammel K, Gyongyossy-Issa MI and Devine DV (2012) Riboflavin and ultraviolet light treatment potentiates VASP-Ser-239 phosphorylation in platelet concentrates during storage, Transfusion, 52(2):397-408.
  7. Schubert P, Coupland D, Culibrk B, Goodrich R and Devine DV (2013) Inhibition of p38-MAPK significantly improves in vitro platelet quality during storage following riboflavin and ultraviolet light treatment, Transfusion, 53(12):3164-73.
  8. Chen Z, Schubert P, Culibrk B, Devine DV (2015) p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment, Transfusion, 55(4):848-57.
  9. Devine DV, Schubert P (2016) Pathogen inactivation technologies: the advent of pathogen-reduced blood components to reduce blood safety risk, Hematol Oncol Clin North Am, 30(3):609-17.
  10. Schubert P, Culibrk B, Karwal S, Goodrich RP, Devine DV (2016) Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment, Proteomics Clin Appl, 10(8):839-50.
  11. Arbaeen AF, Schubert P, Serrano K, Carter CJ, Culibrk B, Devine DV (2017) Pathogen inactivation treatment of plasma and platelet concentrates and their predicted functionality on massive transfusion protocols, Transfusion, 57(5):1208-17.
  12. Chen Z, Schubert P, Culibrk B, Bakkour S, Busch MP, Devine DV (2017) p38 MAPK regulates mitochondrial function and microvesicel release in riboflavin/UV light-treated apheresis platelet concentrates, Transfusion, 57(5):1199-1207.
  13. Qadri SM, Chen D, Schubert P, Perruzza DL, Bhakta V, Devine DV, Sheffield WP (2017) Pathogen inactivation by riboflavinand ultraviolet illumination accelerates the red blood cell storage lesion and promotes eryptosis, Transfusion, 57(3):661-73.
  14. Schubert P, Karwal S, Culibrk B, Serrano K, Levin E, Yi QL, Thiele T, Greinacher A, Marschner S, Devine DV (2017) Altered timing of riboflavin/UV light treatment improves platelet quality, Transfusion, 57(8):2026-34.
  15. Schubert P, Johnson L, Marks DC, Devine DV (2018) Ultraviolet-based pathogen inactivation systems: Untangling the molecular targets activated in platelets; Front Med, 7(5):129.
  16. Schubert P, Culibrk, B, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich R, Yoshida T, Devine DV (2019) Removal of oxygen from whole blood prior to riboflavin/UV light pathogen inactivation improves red blood cell in vitro quality during storage, Transfusion, 59(10):3197-3204.
  17. Johnson L, Schubert P, Tan S, Devine DV, Marks DC (2016) Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution, Transfusion, 56(2):360-68.
  18. Schubert P, Culibrk B, Karwal S, Serrano K, Levin E, Bu D, Bhakta V, Sheffield WP, Goodrich RP, Devine DV. (2015) Whole blood treated with riboflavin and ultraviolet light: quality assessment of all blood components produced by the buffy coat method, Transfusion, 55(4):815-23.
  19. Schubert P, Thon JN, Duguay M, Serrano K, Lin S, Kast J and Devine DV (2008) Discovery of protein changes during platelet storage is facilitated by complementary proteomic approaches, Transfusion, 48(3):425-35.
  20. Thon JN, Schubert P, and Devine DV (2008) Platelet storage (lesion): A new understanding from a proteomic perspective, Transfus. Med. Rev, 22(4):268-79.
  21. Schubert P, Thon JN, Walsh GM, Chen CH, Moore ED, Devine DV and Kast J (2009) A signaling pathway contributing to platelet storage lesion development: Targeting PI3-kinase-dependent Rap1 activation slows storage-induced platelet deterioration, Transfusion, 49(9):1944-55.
  22. Schubert P and Devine DV (2010) Proteomics meets blood banking: Identification of targets for the improvement of platelet quality, J Proteomics, 73(3):436-444.
  23. Schubert P and Devine DV (2010) De novo protein synthesis in mature platelets: A consideration for transfusion medicine, Vox sang, 99(2):112-22.
  24. Chen D, Schubert P, Devine DV (2017) Identification of potential protein markers in pathogen inactivated and gamma-irradiated red cell concentrates, Proteomics Clin Appl, 11(7-8).
  25. Qadri S, Chen D, Schubert P, Devine DV, Sheffield WP (2017) Early γ-irradiation and subsequent storage of red cells in SAG-M additive solution potentiates the storage lesion and susceptibility to apoptotic cell death, Vox sang, 112(5):480-3.
  26. Taha M, Kalah M, Yi QL, Maurer E, Jenkins C, Schubert P, Ramirez-Arcos S, Bacterial survival and distribution during buffy coat platelet production, Vox sang, 111(4):333-40.
  27. Taha M, Culibrk B, Kalab M, Schubert P, Yi QL, Goodrich R, Ramirez-Arcos S (2017) Efficiency of riboflavin and UV light treatment to inactivate S. epidermis biofilms in buffy coat platelet concentrates, Vox sang, 112(5):408-16.
  28. Sutherland MR, Simon AY, Serrano K, Schubert P, Acker JP, Pryzdial EL (2016) Dengue virus persists and replicates during storage of platelet and red cell units, Transfusion, 56(5): 1129-37.



  • Research Associate, Canadian Blood Services, Vancouver, British Columbia, Canada (2006-2020)
  • Postdoctoral Fellow, Proteomics, Biomedical Research Centre, University of British Columbia, Vancouver, Canada (2004-2006)
  • Postdoctoral Fellow, Cell Biology, Biomedical Research Centre, University of British Columbia, Vancouver, Canada (2001-2003)
  • PhD, Biochemistry and Microbiology, University of Erlangen, Germany (1996-2001)
  • MSc, Chemistry, University of Erlangen, Germany (1989-1996)