Karen Cheung

Contact InformationKaren Cheung
Life Sciences Centre
#4305 – 2350 Health Sciences Mall
Vancouver, BC, Canada V6T 1Z3
Office: KAIS 3064
Fax: 1-604-822-7135
Email: kcheung@ece.ubc.ca
Website: http://www.ece.ubc.ca/~kcheung

Research Interests

  • Biomedical Technologies.
  • Emerging Micro/Nano Technologies.

Selected Publications

  1. Luan, Enxiao, Hossham Shoman, Daniel M Ratner, Karen C. Cheung, Lukas Chrostowski. “Silicon Photonic Biosensors Using Label-Free Detection”. (MDPI), 2018. 18(10):3519. https://doi.org/10.3390/s18103519.
  2. Laplatine, Loic, Enxiao Luan, Karen Cheung, Daniel M Ratner, Yonathan Dattner, Lukas Chrostowski. “System-level integration of active silicon photonic biosensors using Fan-Out Wafer-Level-Packaging for low cost and multiplexed point-of-care diagnostic testing”. Sensors and Actuators B: Chemical. (Elsevier), 2018. 273:1610-1617. https://doi.org/10.1016/j.snb.2018.07.025.
  3. Luan, Enxiao, Han Yun, Loic Laplatine, Yonathan Dattner, Daniel M Ratner, Karen C. Cheung, Lukas Chrostowski. “Enhanced Sensitivity of Subwavelength Multibox Waveguide Microring Resonator Label-Free Biosensors”. IEEE Journal of Selected Topics in Quantum Electronics. (IEEE), 2018. 25(3):1-11. DOI: 10.1109/JSTQE.2018.2821842.
  4. Karamikamkar, Solmaz, Ehsan Behzadfar, and Karen C. Cheung. “A novel approach to producing uniform 3-D tumor spheroid constructs using ultrasound treatment”. Biomedical Microdevices, (Springer) 20(2):27. doi: 10.1007/s10544-018-0260-1.
  5. Wang, Lingyu, Linfen Yu, Samantha Grist, Karen C. Cheung, David D.Y. Chen. “Different in vitro cellular responses to tamoxifen treatment in polydimethylsiloxane-based devices compared to normal cell culture”. Journal of chromatography. B. (Elsevier), 2017. 1068-1069:105-111. doi: 10.1016/j.jchromb.2017.09.041.
  6. Casanova-Moreno, Jannu, Josiah To, Cheng Wei Tony Yang, Robin B. Turner, Dan Bizzotto, Karen C. Cheung. “Fabricating devices with improved adhesion between PDMS and gold-patterned glass”. Sensors and Actuators B – Chemical. (Elsevier), 2017. 246:904-909. doi: 10.1016/j.snb.2017.02.109.
  7. Noel, Adam, Karen C. Cheung, Robert Schober, Dimitrios Makrakis, Abdelhakim Hafid. “Simulating with AcCoRD: Actor-Based Communication via Reaction-Diffusion”. Nano Communication Networks. (Elsevier), 2017. 11:44-75. doi: 10.1016/j.nancom.2017.02.002.
  8. Deng, Yansha, Adam Noel, Maged Elkashlan, Arumugam Nallanathan, and Karen C. Cheung, “Modeling and Simulation of Molecular Communication Systems with a Reversible Adsorption Receiver”. IEEE Transactions on Molecular, Biological, and Multi-Scale Communications (IEEE), 2016. 1(4):347-362. doi: 10.1109/TMBMC.2016.2589239.
  9. Grist, Samantha, S. Soroush Nasseri, Tak Poon, Calvin Roskelley, and Karen C. Cheung. “On‐chip clearing of arrays of 3-D cell cultures and micro‐tissues”. Biomicrofluidics (American Institute of Physics), 2016. 10:044107. doi:10.1063/1.4959031.
  10. Jonas FlueckigerShon Schmidt, Valentina Donzella, Ahmed Sherwali, Daniel M. Ratner, Lukas Chrostowski, Daniel M. Ratner, Karen C. Cheung. “Sub-wavelength grating for enhanced ring resonator biosensor”. Optics Express (OSA), 2016.24(14):15672-86. doi: 10.1364/OE.24.015672.
  11. Cheng, Eric, Haoran YuAli Ahmadi, and Karen C. Cheung. “Investigation of the Hydrodynamic Response of Cells in Drop on Demand Piezoelectric Inkjet Nozzles”. (IOP Science) 2016. 8:015008. doi:10.1088/1758-5090/8/1/015008.
  12. Grist, Samantha M., Jonathan C. Schmok, Meng-Chi (Andy) Liu, Lukas Chrostowski, and Karen C. Cheung. “Designing a Microfluidic Device with Integrated Ratiometric Oxygen Sensors for the Long-Term Control and Monitoring of Chronic and Cyclic Hypoxia”. (MDPI) 2015. 15: 20030-20052. doi:10.3390/s150820030.
  13. Noel, Adam, Karen C. Cheung, and Robert Schober. “Joint Channel Parameter Estimation via Diffusive Molecular Communication”. IEEE Transactions on Molecular, Biological, and Multi-Scale Communications. (IEEE) 1(1): 4-17. doi: 10.1109/TMBMC.2015.2465511.
  14. Cheng, Eric, Ali Ahmadi,and Karen C. Cheung. “Measurement of the Oscillatory Flow Field inside Tapered Cylindrical Inkjet Nozzles Using Micro-Particle Image Velocimetry “. Microfluidics and Nanofluidics. (Springer) 2015. 19(3): 635-646. doi: 10.1007/s10404-015-1589-x.
  15. Yu, Linfen, Eric Cheng, Samantha M. Grist, Yi-Chin Eugene Hwang, Cynthia Ni, and Karen C. Cheung. “Core-shell hydrogel beads with extracellular matrix for tumor spheroid formation”. (American Institute of Physics) 2015. 024118 doi: 10.1063/1.4918754.
  16. Yu, Linfen, Cynthia Ni, Samantha M. Grist, Carmen Bayly, and Karen C. Cheung. “Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening”. Biomedical Microdevices, (Springer) 17(2):33. doi: 10.1007/s10544-014-9918-5.
  17. Noel, Adam, Karen C. Cheung, and Robert Schober. “A Unifying Model for External Noise Sources and ISI in Diffusive Molecular Communication”. IEEE Journal on Selected Areas in Communications. (IEEE) 32(12):2330-2343. doi: 10.1109/JSAC.2014.2367693.
  18. Grist, Samantha M., Nominerdene Oyunerdene, Jonas FlueckigerJohn Kim, Philip C. Wong, Lukas Chrostowski, and Karen C. Cheung. “Fabrication and laser patterning of polystyrene optical oxygen sensor films for lab-on-a-chip applications”. (Royal Society of Chemistry) 2014. 139(22):5719-5728. doi: 10.1039/c4an00765d.
  19. Noel, Adam, Karen C. Cheung, and Robert Schober. “Optimal Receiver Design for Diffusive Molecular Communication with Flow and Additive Noise”. IEEE Transactions on Nanobioscience. (IEEE) 2014.13(3):350-362. doi: 10.1109/TNB.2014.2337239.
  20. Ouellet, EricEric T. Lagally, Karen C. Cheung, Charles A. Haynes. “A simple method for eliminating fixed-region interference of aptamer binding during SELEX”. Biotechnology and Bioengineering. (Wiley) 111(11):2265–2279. doi: 10.1002/bit.25294.
  21. Winer, Michael, Ali Ahmadi, and Karen C. Cheung. “Application of a three-dimensional (3D) particle tracking method to microfluidic particle focusing”. Lab on a Chip. (Royal Society of Chemistry) 14(8):1443-51. doi: 10.1039/C3LC51352A.
  22. Noel, Adam, Karen C. Cheung, and Robert Schober. “Improving Receiver Performance of Diffusive Molecular Communication with Enzymes”. IEEE Transactions on Nanobioscience. (IEEE) 13(1):31-43. doi: 10.1109/TNB.2013.2295546.
  23. Wang, Xu, Jonas Flueckiger, Shon A. Schmidt, Samantha M. Grist, Sahba T. Fard, James T. Kirk, Matt Doerfler, Karen C. Cheung, Daniel M. Ratner, and Lukas Chrostowski. “A novel silicon photonic biosensor using phase-shifted Bragg gratings in slot waveguide”. Journal of Biophotonics. (Wiley) 6(10):821-828. doi: 10.1002/jbio.201300012.
  24. Grist, Samantha M.Shon A. Schmidt, Jonas FlueckigerValentina Donzella, Wei Shi, Sahba Talebi Fard, James T. Kirk, Ali Ayazi, Tom Baehr-Jones, Michael Hochberg, Daniel M. Ratner, Karen C. Cheung, and Lukas Chrostowski. “Silicon photonic micro-disk resonators for label-free biosensing”. Optics Express. (OSA)21(7) (2013) 7994-8006. doi: 10.1364/OE.21.007994.
  25. Chahal, Daljeet, Ali Ahmadi, and Karen C. Cheung. “Improving Piezoelectric Cell Printing Accuracy and Reliability through Neutral Buoyancy”. Biotechnology and Bioengineering. (Wiley) 109(11):2932-40. doi: 10.1002/bit.24562.
  26. Han, Dong and Karen C. Cheung. “Biodegradable Cell-Seeded Nanofiber Scaffolds for Neural Repair”. (MDPI) 3(4) (2011) 1684-1733. doi: 10.3390/polym3041684.
  27. Flueckiger, Jonas, Vahid Bazargan, Boris Stoeber, and Karen C. Cheung. “Characterization of Postfabricated Parylene C Coatings inside PDMS Microdevices”. Sensors and Actuators B – Chemical. (Elsevier)160(1) (2011) 864-874doi: 10.1016/j.snb.2011.08.073.
  28. Grist, Samantha, Lukas Chrostowski,and Karen C. Cheung. “Optical Oxygen Sensors for Applications in Microfluidic Cell Culture”. (MDPI) 10(10) (2010) 9286-9316. doi:10.3390/s101009286.
  29. Yu, Linfen, Michael C.W. Chen, and Karen C. Cheung. “Droplet-Based Microfluidic System for Multicellular Tumor Spheroid Formation and Anticancer Drug Testing”. Lab on a Chip, (Royal Society of Chemistry) 10(18) (2010) 2424-2432. doi: 10.1039/c004590j.
  30. Cheung, Karen C., Marco Di Berardino, Grit Schade-Kampmann, Monika Hebeisen, Arkadiusz Pierzchalski, Jozsef Bocsi, Anja Mittag, Attila Tárnok. “Microfluidic impedance-based flow cytometry”. Cytometry A. (Wiley) 77(7) (2010) 648-666. doi: 10.1002/cyto.a.20910.


  • Postdoc, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2005.
  • Ph.D., Bioengineering, University of California, Berkeley, USA, 2002.
  • B.S., Bioengineering, University of California, Berkeley, USA, 1998.