Hugh Kim

Contact Information
Life Sciences Centre
#4.303 – 2350 Health Sciences Mall
Vancouver, BC, Canada V6T1Z3
Tel: 1-604-827-4356
Fax: 1-604-822-7742
Email: hughkim@dentistry.ubc.ca

Current Positions

  • Assistant Professor, Faculty of Dentistry, UBC.
  • Principal Investigator, Centre for Blood Research, UBC.
  • Associate Member, Department of Biochemistry and Molecular Biology.

Research Interests

Biochemical signalling mechanisms that regulate platelet function.

Publications

  1. Liu KYP, Lu XJD, Zhu YS, Le N, Kim H, Poh C. Plasma-derived inflammatory proteins predicts oral squamous cell carcinoma, Front. Oncol., in press.
  2. De Silva E, Kim H. Drug-induced thrombocytopenia: focus on platelet apoptosis. Chem. Biol. Interact. 2018 Mar 25;284:1-11.
  3. Brousseau-Nault M, Kizhakkedathu JN, Kim H. Chronic periodontitis is associated with platelet factor 4 (PF4) secretion: a pilot study. J. Clin. Periodontol. 2017 Nov;44(11):1101-1111.
  4. Javaid M, Biddle C, Tsai CM, Hakkinen L, Kim H. Platelet factor 4 upregulates MMP-1 production in gingival fibroblasts. J. Periodontal Res. 2017 Aug;52(4):787-792.
  5. Cines DB, Yarovoi SV, Zaitsev S, Lebedeva T, Rauova L, Poncz M, Arepally GM, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Polyphosphate- platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia. Blood Adv. 2016 Nov 22;1(1):62-74.
  6. Wijeyewickrema LC, Lameignere E, Hor L, Duncan RC, Shiba T, Travers RJ, Lei V, Smith SA, Kim H, Morrissey JH, Pike RN, Conway EM. Polyphosphate is a novel cofactor for regulation of the classical pathway of complement by the serpin, C1-inhibitor. Blood. 2016 Sep 29;128(13):1766-76.
  7. Kim H, Falet H, Hoffmeister KM, Hartwig JH. Wiskott Aldrich Syndrome protein (WASp) controls the delivery of platelet transforming growth factor-beta 1 (TGF-b1), J. Biol. Chem. 2013;Nov 29;288(48):34352-63.

Education

  • Postdoc, Harvard University.
  • Ph.D., University of Toronto, 2010.
  • M.Sc., University of British Columbia.
  • Dip Perio, University of British Columbia, 2004.
  • Dental residency, Mount Sinai Hospital, Toronto.
  • DMD, University de Montreal, 2000.