Fabio Rossi

Contact InformationFabio Rossi
The Biomedical Research Centre
2222 Health Sciences Mall
Vancouver, BC, Canada V6T 1Z3
Tel 1-604-822-7138
Fax 1-604-822-7815
fabio@brc.ubc.ca

Current Positions

  • Co-Director,Biomedical Research Centre
  • Professor, Medical Genetics, Medicine

Research Interests

  • Hematopoietic stem cell migration
  • Stem cell plasticity
  • The role of microglial cells in neurodegenerative disease
  • Chromatin organization and lineage choice

Publications

  1. Lemos DR, Paylor B, Chang C, Sampaio A, Underhill TM, Rossi FM. Functionally convergent white adipogenic progenitors of different lineages participate in a diffused system supporting tissue regeneration. Stem Cells. 2012 Jun;30(6):1152-62.
  2. Long MA, Rossi FM. Targeted cell fusion facilitates stable heterokaryon generation in vitro and in vivo. PLoS One. 2011;6(10):e26381.
  3. Alfaro LA, Dick SA, Siegel AL, Anonuevo AS, McNagny KM, Megeney LA, Cornelison DD, Rossi FM. CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration. Stem Cells. 2011 Dec;29(12):2030-41.
  4. Comeau PA, Frei H, Yang C, Fernlund G, Rossi FM. In Vivo Evaluation of Calcium Polyphosphate for Bone Regeneration. J Biomater Appl. 2011 Sep 16. [Epub ahead of print]
  5. Lehnertz B, Rogalski JC, Schulze FM, Yi L, Lin S, Kast J, Rossi FM. p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice. Mol Cell. 2011 Aug 19;43(4):673-80.
  6. Ajami B, Bennett JL, Krieger C, McNagny KM, Rossi FM. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci. 2011 Jul 31;14(9):1142-9. doi: 10.1038/nn.2887.
  7. Sekulovic S, Gylfadottir V, Vulto I, Gasparetto M, Even Y, Brookes C, Smith C, Eaves CJ, Lansdorp PM, Rossi FM, Humphries RK. Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells. Blood. 2011 Aug 18;118(7):1766-73.
  8. Knight DA, Rossi FM, Hackett TL. Mesenchymal stem cells for repair of the airway epithelium in asthma. Expert Rev Respir Med. 2010 Dec;4(6):747-58.
  9. Even Y, Bennett JL, Sekulovic S, So L, Yi L, McNagny KM, Humphries RK, Rossi FM. NUP98-HOXA10hd-expanded hematopoietic stem cells efficiently reconstitute bone marrow of mismatched recipients and induce tolerance. Cell Transplant. 2010 Nov 19.
  10. Natarajan A, Lemos DR, Rossi FM. Fibro/adipogenic progenitors: A double-edged sword in skeletal muscle regeneration. Cell Cycle. 2010 Jun 19;9(11).
  11. Grassl GA, Faustmann M, Gill N, Zbytnuik L, Merkens H, So L, Rossi FM, McNagny KM, Finlay BB. CD34 mediates intestinal inflammation in Salmonella-infected mice. Cell Microbiol. 2010 Nov;12(11):1562-75.
  12. Lehnertz B, Northrop JP, Antignano F, Burrows K, Hadidi S, Mullaly SC, Rossi FM, Zaph C. Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function. J Exp Med. 2010 May 10;207(5):915-22.

Education

  • Postdoctorate (Molecular Pharmacology), Standford University Medical Center, USA, 1996 – 1999
  • Ph.D.(Molecular Biology), European Molecular Biology Lab, Germany, 1992 – 1996
  • M.D., Università Degli Studi di Genova, Italy, 1985 – 1991

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