Publications

Busting Deadly Blood Clots: Using siRNA Gene Therapy as a New Approach

Busting Deadly Blood Clots: Using siRNA Gene Therapy as a New Approach

Blood clots play a part in many severe health issues, from causing strokes and heart attacks to influencing neurodegenerative diseases like Alzheimer’s. We chatted with lead authors Dr. Christian Kastrup and PhD Candidate Amy Wong Strilchuk about their research, and how their findings might help dissolve clots safely.

An illustration of the SARS-CoV-2 virus, created by the Centers for Disease Control and Prevention (CDC). Image source.

Predicting the Evolution of SARS-CoV-2 Proteins: Insights into Ongoing COVID-19 Research at the CBR

The overarching goal of this work is to the predict and identify potentially detrimental mutations in SARS-CoV-2 using a combination of artificial intelligence, sequence-based prediction algorithms, and atomic resolution structural biology.

Just Keep Swarming

Just Keep Swarming

Members of the Hancock lab recently published a study detailing the multidrug adaptative antibiotic resistance of P. aeruginosa swarming cells. They explored the role of swarming in the development of resistance to a variety of antibiotics, and the genetic mechanisms behind this adaptive resistance.

New algorithm can identify cells that humans can’t

New algorithm can identify cells that humans can’t

Researchers at the University of British Columbia have developed an algorithm that can accurately identify different types of cells pictured in microscope photos, even when those cells are indistinguishable to the human eye.

UBC researcher helps map the human proteome

UBC researcher helps map the human proteome

With 90 per cent of the proteins in the human body now mapped, Overall says scientists have a deeper understanding of how individual proteins interact to influence human health, providing insights into disease prevention and individualized medicine.

Fast and Furious: Targeting “nitro(gen) boosts” in a deadly bacterium for next-generation antimicrobials

Fast and Furious: Targeting “nitro(gen) boosts” in a deadly bacterium for next-generation antimicrobials

What if bacteria also had the ability to use nitrogen for a “boost”? Alford et al. recently examined the role of a two-component system called NtrBC in Pseudomonas aeruginosa.