John Wu

Contact InformationJohn Wu
Division of Oncology/Hematology/BMT
BC Children’s Hospital and BC Women’s Hospital & Health Centre
#A123B, 4480 Oak Street
Vancouver, BC, Canada, V6H 3V4
Tel: 1-604-875-2406
Fax: 1-604-875-2911
Email: jwu@cw.bc.ca

Current Positions

  • Clinical Professor, Hematology and Oncology, Pediatrics, Medicine.
  • Clinical Investigator, Child and Family Research Institute (CFLI).

Research Interests

Investigation of Clotting Factor Heterogeneity in Severe Hemophilia A 
The focus of this research is to develop a sensitive assay to accurately measure circulating Factor VIII levels between 0 and 1%, based on measurement of the activity of the enzyme, thrombin, which develops in proportion to the level of FVIII activity present. Three aspects of hemophilia treatment will then be investigated with participation from clinics across Canada.

Blood Borne Pathogen Surveillance Project 
The Association of Hemophilia Directors of Canada has been asked to develop a method to look for known and emerging blood borne diseases. This cross-Canada project will establish a secure bank of samples to test for known blood borne infectious agents and genetic changes causing or modifying the clotting disease, and that will be available for testing for newly discovered viruses and clotting gene changes as they are found.

Publications

  1. Dwinnell SJ, Coad S, Butler B, Albersheim S, Wadsworth LD, Wu JK, Delisle MF. In Utero diagnosis and management of a fetus with homozygous α-Thalassemia in the second trimester: a case report and literature review. J Pediatr Hematol Oncol. 2011 Dec;33(8):e358-60.
  2. Waye JS, Patterson M, Walker L, Eng B, Nakamura LM, Lafferty JD, Yong SL, Wu JK, Chui DH. Beta-thalassemia in association with a new delta-chain hemoglobin variant [delta116(g18)Arg–>Leu]: implications for carrier screening and prenatal diagnosis. Am J Hematol. 2003 Nov;74(3):179-81.
  3. Oliveira M, Steinbok P, Wu J, Heran N, Cochrane D. Spontaneous resolution of calvarial eosinophilic granuloma in children. Pediatr Neurosurg. 2003 May;38(5):247-52.
  4. Gow KW, Murphy III, JJ, Wu JK, deSa DJ. Two cases of rhabdomyosarcoma presenting as metastases to the testicle. J Pediatr Surg. 2003 Aug;38(8):E1-3.

Education