Elisabeth Maurer-Spurej

Contact InformationElisabeth Maurer-Spurej
UBC Centre for Blood Research
Life Sciences Centre
#4466, 2350 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
Tel 1-604-827-5993
Fax 1-604-822-7135
emaurer@interchange.ubc.ca
elisabeth.maurer@blood.ca
Lab Website: http://www.bloodservices.ca/CentreApps/Internet/UW_V502_MainEngine.nsf/page/RDbioMaurer?OpenDocument

Current Positions

  • Clinical Associate Professor, Pathology and Laboratory Medicine
  • Adjunct Scientist, R&D Canadian Blood Services
  • President & CTO, LightIntegra Technology Inc.

Research Interests

Development and evaluation of new methods of detection for platelet function in the context of transfusion medicine or clinical pathology of bleeding disorders; Dynamic light scattering and its application in platelet quality control, microparticle and bacterial detection, characterization of formulations for liposomal drug delivery and protein biochemistry; Determination of platelet serotonin, specifically in genetic disorders and the effect of selective serotonin reuptake inhibitor (SSRI) antidepressants; Application of biophysical techniques for analysis and understanding of platelet quality and platelet-related diseases. This has resulted in a novel, clinically relevant technology, commercialized as ThromboLUX (www.lightintegra.com) to assess the quality of platelets prior to transfusion.

Publication

1. Greco CA, Maurer-Spurej E, Scott MD, Kalab M, Nakane N, Ramírez-Arcos SM. PEGylation prevents bacteria-induced platelet activation and biofilm formation in platelet concentrates. Vox Sang. 2011 Apr;100(3):336-9.

2. Lacroix R, Robert S, Poncelet P, Kasthuri RS, Key NS, Dignat-George F; ISTH SSC Workshop. Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop. J Thromb Haemost. 2010 Nov;8(11):2571-4.

3. Xu Y, Nakane N, Maurer-Spurej E. Novel test for microparticles in platelet-rich plasma and platelet concentrates using dynamic light scattering. Transfusion. 2011 Feb;51(2):363-70.

4. Madsen EH, Saw J, Kristensen SR, Schmidt EB, Pittendreigh C, Maurer-Spurej E. Long-term aspirin and clopidogrel response evaluated by light transmission aggregometry, VerifyNow, and thrombelastography in patients undergoing percutaneous coronary intervention. Clin Chem. 2010 May;56(5):839-47.

Education

  • Ph.D.(Chemistry) Karl-Franzens University Graz, Austria, 1991
  • Mster (Chemistry) Karl-Franzens University Graz, Austria, 1988

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