Publications

Some of the members of Dr. Karsan's lab studying MDS. Left to Right: Dr. Suzanne Vercauteren (former Hematopathology resident); Dr. Dan Starczynowski, post-doctoral fellow; Sandy Sung, technician.

Karsan group identify microRNAs that are important in a maligant blood disease

A study published in Nature Medicine, led by CBR investigator Aly Karsan, Professor and Medical Director of the Cancer Genetics Laboratory, BCCA, and Head of Clinical Genomic Diagnostics at the Genome Sciences Centre reveals the role of two microRNAs (miRs) in a subtype of myelodysplastic syndromes (MDS). MDS comprise a group of malignant hematopoietic stem […]

Kelly McNagny and colleagues in a multilab study uncover mysteries of vascular lumen formation

Kelly McNagny and colleagues in a multilab study uncover mysteries of vascular lumen formation

The survival of mammals requires the formation of a complex network of blood vessels – tubes that are lined by endothelial cells – that traverse every organ, and dynamically respond to a range of pathophysiologic stresses. The blood vessels carry and regulate the delivery of essential factors including oxygen, nutrients and fluids, and dispose of […]

Overall lab provides perspectives into multitasking proteins

Overall lab provides perspectives into multitasking proteins

The cover artwork represents Popper’s postulate: If several observations of swans always show swans to be white, then the conclusion is that all swans are white. The dogma that all swans are white, held until the discovery in the eighteenth-century of black swans in Australia. We used this as an analogy for the interpretation of […]